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KMID : 0604520230490020183
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Journal of the Society of Cosmetic Scientists of Korea
2023 Volume.49 No. 2 p.183 ~ p.192
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A Study on the Skin Improvement of Ethanol and Hot Water Extracts from Scutellaria baicalensis
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Cho Seong-Mi
Won Yu-Rim
Park Jin-Oh
Lee Hye-Ja
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Abstract
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In this study, we investigated the antioxidant activity, anti-inflammatory activity, whitening, moisturizing, wound-healing, cell proliferation and cell protective effects of 70% EtOH and hot water extract from Scutellaria baicalensis.
For the anti-oxidative test, the 70% EtOH and hot water extract showed DPPH radical scavenging activities. In the anti-inflammatory tests, 70% EtOH and hot water extract inhibited the production of NO, pro-inflammatory cytokine (IL-6) and prostaglandin (PGE2). In addition, it was confirmed that the 70% EtOH and hot water extract inhibited the melanin production, and increased production of hyaluronic acid (HA), a moisturizing factor. As a result of cell migration and proliferation assay, 70% EtOH extract promoted the cell growth in HaCaT cell. Additionally, 70% EtOH and hot water extract showed cell protective effects against UVB, and 70% EtOH extract also showed cell protective effects agianst blue light. Based on these results, it is concluded that the 70% EtOH and hot water extract from Scutellaria baicalensis could be potentially applicable as anti-oxdiative, anti-inflammation, whitening, moisturizing, wound-healing, cell proliferation and cell protective effects in cosmetic natural materials.
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KEYWORD
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Scutellaria baicalensis, anti-inflammatory, moisturizing, wound healing, UVB
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